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KMID : 1025520150570010031
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Journal of Animal Science and Technology
2015 Volume.57 No. 1 p.31 ~ p.31
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Association of Insulin-like growth factor binding protein 2 genotypes with growth, carcass and meat quality traits in pigs
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Prasongsook Sombat
Choi Igseo
Bates Ronald O.
Raney Nancy E.
Ernst Catherine W.
Tumwasorn Sornthep
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Abstract
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Background: This study was conducted to investigate the potential association of variation in the insulin-like growth factor binding protein 2 (IGFBP2) gene with growth, carcass and meat quality traits in pigs. IGFBP2 is a member of the insulin-like growth factor binding protein family that is involved in regulating growth, and it maps to a region of pig chromosome 15 containing significant quantitative trait loci that affect economically important trait phenotypes.
Results: An IGFBP2 polymorphism was identified in the Michigan State University (MSU) Duroc?×?Pietrain F2 resource population (n?=?408), and pigs were genotyped by MspI PCR-RFLP. Subsequently, a Duroc pig population from the National Swine Registry, USA, (n?=?326) was genotyped using an Illumina Golden Gate assay. The IGFBP2 genotypic frequencies among the MSU resource population pigs were 3.43, 47.06 and 49.51 % for the AA, AB and BB genotypes, respectively. The genotypic frequencies for the Duroc pigs were 9.82, 47.85, and 42.33 % for the AA, AB and BB genotypes, respectively. Genotype effects (P?
Conclusions: Results of this study revealed associations of the IGFBP2 genotypes with growth, carcass and meat quality traits in pigs. The results indicate IGFBP2 as a potential candidate gene for growth rate, backfat thickness, loin muscle area and some pork quality traits.
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KEYWORD
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IGFBP2, Growth, Meat quality, Pig
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